诊疗指南

AABB血小板输注的临床实践指南

Platelet Transfusion: A Clinical Practice Guideline From the AABB
2015-02-13 16:04 点击次数:909发表评论

Approximately 2.2 million platelet doses are transfused annually in the United States . A high proportion of these platelet units are transfused prophylactically to reduce the risk for spontaneous bleeding in patients who are thrombocytopenic after chemotherapy or hematopoietic progenitor cell transplantation (HPCT). Unlike other blood components, platelets must be stored at room temperature, limiting the shelf life of platelet units to only 5 days because of the risk for bacterial growth during storage. Therefore, maintaining hospital platelet inventories is logistically difficult and highly resource-intensive. Platelet transfusion is associated with several risks to the recipient, including allergic reactions and febrile nonhemolytic reactions. Sepsis from a bacterially contaminated platelet unit represents the most frequent infectious complication from any blood product today. In any situation where platelet transfusion is being considered, these risks must be balanced against the potential clinical benefits.

    
学科代码:内科学   关键词:血小板输注 ,指南 爱思唯尔医学网, Elseviermed
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