急需同等资金来支持评估循证和指南推荐结直肠癌筛查试验的研究
In colorectal (CRC) screening guidelines published before 2008, flexible sigmoidoscopy (FS) plus fecal occult blood test (FOBT) was a recommended option. In 2008 the American Cancer Society/US Multisociety Taskforce and American College of Radiology guidelines5 dropped this recommendation and the US Preventive Services guidelines (USPSTF)6 changed its recommendation to FS and high-sensitivity FOBT (Hemoccult Sensa [Beckman Coulter, Inc, Fullerton, CA] or Fecal Immunochemical Test [FIT]) every 5 years plus an interval high-sensitivity FOBT alone every 3 years from age 50 to age 75.6 The importance and impact of guidelines make it necessary to evaluate the evidence available to guideline maker
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