雷帕霉素可延长小鼠寿命但限制对衰老的影响

Rapamycin extends murine lifespan but has limited effects on aging
作者:Frauke Neff
期刊: J CLIN INVEST2013年1月8期123卷

Introduction

Aging is an important risk factor for a number of disorders and functional impairments. Therapeutic targeting of the aging process may therefore represent an innovative strategy in the quest for novel and potentially broadly effective treatments against diseases associated with old age, including neurodegenerative diseases, cardiovascular diseases, cancers, and type 2 diabetes mellitus (1).

The vast majority of current research that aims to identify novel anti-aging interventions uses lifespan measures as a primary readout to detect anti-aging effects. Mechanisms involved in cell growth and metabolism are commonly implicated players in lifespan regulation (2). Specifi


学科代码:其他   关键词:none
来源: J Clin Invest.
顶一下(0
您可能感兴趣的文章
    发表评论网友评论(0)
      发表评论
      登录后方可发表评论,点击此处登录