特别人群(REVEAL肺动脉高压预测模型和长期生存预测的应用

Validation of the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) pulmonary hypertension prediction model in a unique population and utility in the prediction of long-term survival

2012-10-31 15:54点击：133次发表评论

作者：Rebecca Cogswell, MD

期刊： 《J HEART LUNG TRANSPL 》2012年11月11期31卷

Article Outline

Abstract
Methods
- Validation cohort
- Baseline variables
- REVEAL survival probability calculation
- Outcome data
  - Survival
  - Survival or freedom from lung transplant
  - Losses to follow-up
- Statistical methods
Results
- Clinical characteristics
- Model discrimination
- Model calibration
- Long-term survival
Discussion
Disclosure statement
References
Copyright

BACKGROUND

The Registry to Evaluate Early and Long-Term Pulmonary Arterial (PAH) Hypertension Disease Management (REVEAL) model was designed to predict 1-year survival in patients with PAH. Multivariate prediction models need to be evaluated in cohorts distinct from the derivation set to determine external validity. In addition, limited data exist on the utility