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American Journal of Pathology
(AM J PATHOL) 《美国病理学杂志》

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美国病理学杂志
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《美国病理学杂志》,即美国研究病理学会的官方杂志,旨在发表关于疾病细胞和分子生物学的,高质量的原创论文。编辑们接受这样的稿件:提升发病机理、分类、诊断和疾病机制的基础知识和转化知识,而没有偏好为一个特定的分析方法。重点优先的是有关人类疾病的研究和利用细胞、分子、动物、生物、化学和免疫学方法来与形态学结合的相关实验模型的研究。

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Published 2012年9月,Volume 181,Issue 3

最新一期

Article Title Author(s) Pages
This Month in AJP

23 July 2012

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ASIP Centennial Perspective
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The Dark Side of Publishing: Promoting Ethics in AJP 2003 to 2008

30 July 2012

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Jay M. McDonald, Audra E. Cox, Gene P. Siegal 730-732
Review
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Deciphering the Message Broadcast by Tumor-Infiltrating Dendritic Cells

16 July 2012

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Nina Karthaus, Ruurd Torensma, Jurjen Tel 733-742
CME Program Article
Commentary
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ADAMTS5: A New Player in the Vascular Field

23 July 2012

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Liisa Nissinen, Veli-Matti Kähäri 743-745
CME Program Article
Short Communications
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NAD Induces Astrocyte Calcium Flux and Cell Death by ART2 and P2X7 Pathway

09 July 2012

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Jianbiao Wang, Junhua Yang, Puqing Liu, Xiwen Bi, et al. 746-752
Critical Involvement of Macrophage Infiltration in the Development of Sjögren's Syndrome–Associated Dry Eye

05 July 2012

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Delu Zhou, Ying-Ting Chen, Feeling Chen, Marianne Gallup,et al. 753-760
Regular Articles
Animal Models
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Pathological Features in the LmnaDhe/+ Mutant Mouse Provide a Novel Model of Human Otitis Media and Laminopathies

23 July 2012

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Yan Zhang, Heping Yu, Min Xu, Fengchan Han, et al. 761-774
Experimental Autoimmune Breast Failure: A Model for Lactation Insufficiency, Postnatal Nutritional Deprivation, and Prophylactic Breast Cancer Vaccination

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Pavani Kesaraju, Ritika Jaini, Justin M. Johnson, Cengiz Z. Altuntas, et al. 775-784
Targeting BRAFV600E in an Inducible Murine Model of Melanoma

12 July 2012

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Anna I. Hooijkaas, Jules Gadiot, Martin van der Valk, Wolter J. Mooi, et al. 785-794
Biomarkers, Genomics, Proteomics, and Gene Regulation
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CD137 Is Expressed in Follicular Dendritic Cell Tumors and in Classical Hodgkin and T-Cell Lymphomas: Diagnostic and Therapeutic Implications

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Matthew W. Anderson, Shuchun Zhao, Aharon G. Freud, Debra K. Czerwinski, et al. 795-803
Epigenetic Regulation of miR-34a Expression in Alcoholic Liver Injury

26 July 2012

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Fanyin Meng, Shannon S. Glaser, Heather Francis, Fuquan Yang, et al. 804-817
Fibrinogen Excretion in the Urine and Immunoreactivity in the Kidney Serves as a Translational Biomarker for Acute Kidney Injury

23 July 2012

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Dana Hoffmann, Vanesa Bijol, Aparna Krishnamoorthy, Victoria R. Gonzalez, et al. 818-828
CME Program Article
Cardiovascular, Pulmonary, and Renal Pathology
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Respiratory and Olfactory Cytotoxicity of Inhaled 2,3-Pentanedione in Sprague-Dawley Rats

14 August 2012

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Ann F. Hubbs, Amy M. Cumpston, W. Travis Goldsmith, Lori A. Battelli, et al. 829-844
Acute Oral Ethanol Exposure Triggers Asthma In Cockroach Allergen–Sensitized Mice

16 July 2012

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Jacqueline C. Bouchard, Jiyoun Kim, Dominic R. Beal, Louis J. Vaickus, et al. 845-857
Growth Factors, Cytokines, and Cell Cycle Molecules
Article Title Author(s) Pages
The Small Molecule Inhibitor G6 Significantly Reduces Bone Marrow Fibrosis and the Mutant Burden in a Mouse Model of Jak2-Mediated Myelofibrosis

16 July 2012

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Annet Kirabo, Sung O. Park, Heather L. Wamsley, Meghanath Gali,et al. 858-865
A Novel Function of p53: A Gatekeeper of Retinal Detachment

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Hetian Lei, Marc-Andre Rheaume, Jing Cui, Shizuo Mukai, et al. 866-874
Immunopathology and Infectious Diseases
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The Chymase Mouse Mast Cell Protease 4 Degrades TNF, Limits Inflammation, and Promotes Survival in a Model of Sepsis

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Adrian M. Piliponsky, Ching-Cheng Chen, Eon J. Rios, Piper M. Treuting, et al. 875-886
Brucella abortus–Infected Macrophages Modulate T Lymphocytes to Promote Osteoclastogenesis via IL-17

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Guillermo H. Giambartolomei, Romina Scian, Eva Acosta-Rodríguez, Carlos A. Fossati, et al. 887-896
TGF-β–Responsive Myeloid Cells Suppress Type 2 Immunity and Emphysematous Pathology after Hookworm Infection

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Lisa Heitmann, Reena Rani, Lucas Dawson, Charles Perkins,et al. 897-906
Gingival Lymphatic Drainage Protects Against Porphyromonas gingivalis–Induced Bone Loss in Mice

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Lilian E. Mkonyi, Athanasia Bletsa, Anne I. Bolstad, Vidar Bakken, et al. 907-916
Metabolic, Endocrine, and Genitourinary Pathobiology
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Macrophage Migration Inhibitory Factor Is Involved in a Positive Feedback Loop Increasing Aromatase Expression in Endometriosis

03 July 2012

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Véronique Veillat, Valérie Sengers, Christine N. Metz, Thierry Roger, et al. 917-927
Hypercholesterolemia Promotes an Osteoporotic Phenotype

05 July 2012

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Kristine Pelton, Jaclynn Krieder, Danese Joiner, Michael R. Freeman, et al. 928-936
Loss of Dicer Exacerbates Cyclophosphamide-Induced Bladder Overactivity by Enhancing Purinergic Signaling

16 July 2012

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Shu Zhang, Jian-Wei Lv, Ping Yang, Qilin Yu, et al. 937-946
Molecular Pathogenesis of Genetic and Inherited Diseases
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Development of a Lymphangioleiomyomatosis Model by Endonasal Administration of Human TSC2−/− Smooth Muscle Cells in Mice

05 July 2012

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Elena Lesma, Chiaramonte Eloisa, Eleonora Isaia, Vera Grande, et al. 947-960
Myotubularin-Deficient Myoblasts Display Increased Apoptosis, Delayed Proliferation, and Poor Cell Engraftment

30 July 2012

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Michael W. Lawlor, Matthew S. Alexander, Marissa G. Viola, Hui Meng, et al. 961-968
Reduced Expression of Epidermal Growth Factor Receptor, E-Cadherin, and Occludin in the Skin of Flaky Tail Mice Is Due to Filaggrin and Loricrin Deficiencies

16 July 2012

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Kozo Nakai, Kozo Yoneda, Yoichiro Hosokawa, Tetsuya Moriue,et al. 969-977
Neurobiology
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Blockage of Lysophosphatidic Acid Signaling Improves Spinal Cord Injury Outcomes

23 July 2012

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Yona Goldshmit, Rosalia Matteo, Tamar Sztal, Felix Ellett, et al. 978-992
Interference with RhoA–ROCK Signaling Mechanism in Autoreactive CD4+ T Cells Enhances the Bioavailability of 1,25-Dihydroxyvitamin D3in Experimental Autoimmune Encephalomyelitis

16 July 2012

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Ajaib S. Paintlia, Manjeet K. Paintlia, Bruce W. Hollis, Avtar K. Singh, et al. 993-1006
Tumorigenesis and Neoplastic Progression
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KLF6 Loss of Function in Human Prostate Cancer Progression Is Implicated in Resistance to Androgen Deprivation

23 July 2012

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XiaoMei Liu, Alejandro Gomez-Pinillos, Charisse Loder, Enrique Carrillo-de Santa Pau, et al. 1007-1016
Progression to Adrenocortical Tumorigenesis in Mice and Humans through Insulin-Like Growth Factor 2 and β-Catenin

16 July 2012

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Joanne H. Heaton, Michelle A. Wood, Alex C. Kim, Lorena O. Lima, et al. 1017-1033
Dual Inhibition of Met Kinase and Angiogenesis to Overcome HGF-Induced EGFR-TKI Resistance in EGFR Mutant Lung Cancer

11 July 2012

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Shinji Takeuchi, Wei Wang, Qi Li, Tadaaki Yamada,et al. 1034-1043
Overexpression of TG-Interacting Factor Is Associated with Worse Prognosis in Upper Urinary Tract Urothelial Carcinoma

06 July 2012

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Bi-Wen Yeh, Wen-Jeng Wu, Wei-Ming Li, Ching-Chia Li, et al. 1044-1055
ADAMTS5 Functions as an Anti-Angiogenic and Anti-Tumorigenic Protein Independent of Its Proteoglycanase Activity

16 July 2012

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Saran Kumar, Soheila Sharghi-Namini, Nithya Rao, Ruowen Ge 1056-1068
CME Program Article
Recurrent Rearrangement of the PHF1 Gene in Ossifying Fibromyxoid Tumors

16 July 2012

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Samuel Gebre-Medhin, Karolin H. Nord, Emely Möller, Nils Mandahl, et al. 1069-1077
Evidence for Steroidogenic Potential in Human Prostate Cell Lines and Tissues

16 July 2012

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Nigel C. Bennett, John D. Hooper, Duncan Lambie, Cheok S. Lee, et al. 1078-1087
Vascular Biology, Atherosclerosis, and Endothelium Biology
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Group V Secretory Phospholipase A2 Enhances the Progression of Angiotensin II–Induced Abdominal Aortic Aneurysms but Confers Protection against Angiotensin II–Induced Cardiac Fibrosis in ApoE-Deficient Mice

18 July 2012

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Boris B. Boyanovsky, William Bailey, Lauren Dixon, Preetha Shridas,et al. 1088-1098
The Alarmin IL-33 Is a Notch Target in Quiescent Endothelial Cells

17 July 2012

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Eirik Sundlisæter, Reidunn J. Edelmann, Johanna Hol, Jon Sponheim, et al. 1099-1111
Note of Concern
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Note of Concern

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1112
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Frontmatter
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Editorial Board

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A1-A2
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Table of Contents

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A3-A6
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