Peripheral Nerve Disorders

周围神经系统（PNS）病症是严重的神经学症状的原因，包括无力、感觉缺失、疼痛和自主神经功能障碍，它们与残疾、发病率和死亡率相关。这些障碍可能是原发的遗传性或原因不明的单纯性PNS神经病学障碍或中枢神经系统及PNS病状的一部分。多数PNS障碍继发于其他系统障碍并可能是由于治疗原发疾病引起的。目前在分子遗传学、生物化学、免疫学、形态学和生理学等众多领域已获得了重要进展，加强了我们对周围神经损伤的原因及后果的理解。对这些PNS疾病的理解近年来出现了巨大的扩展，并引发了保护和修复周围神经损伤的重要进展。本卷提供了检查、诊断和治疗这些障碍的学术前沿的进展，将引起科研界以及临床神经科学和神经病学界的兴趣。

Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities.