乳腺癌中的组蛋白酪氨酸脱甲基酶

 

Article Outline

• Abstract
• 1. Introduction
• 2. Methods
  • 2.1. Oncomine database
  • 2.2. GOBO database
• 3. Results
  • 3.1. Oncomine database results
  • 3.2. GOBO database results
• 4. Discussion
• Conflicts of interest statement
• Reviewers
• Acknowledgments
• References
• Biography
• Copyright

Abstract 

Histone lysine demethylases (KDMs) have been recently discovered in mammals and have been nicknamed “erasers” for their ability to remove methyl groups from histone substrates. In cancer cells, KDMs can activate or repress gene transcription, behaving as oncogenes or tu