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Clinical Summaries

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Circulation: Clinical Summaries: Original Research Put Into Perspective for the Practicing Clinician
Circulation. 2012;126:789-790, doi:10.1161/CIR.0b013e31826b7bc1
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Editorials

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Atrial Fibrillation Monitoring: Mathematics Meets Real Life
- Gerhard Hindricks and
- Christopher Piorkowski
Circulation. 2012;126:791-792, published online before print July 23 2012,doi:10.1161/CIRCULATIONAHA.112.124735
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Out-of-Hospital Cardiac Arrest: Getting Beyond the Tip of the Iceberg
- Leonard Ilkhanoff and
- Jeffrey J. Goldberger
Circulation. 2012;126:793-796, published online before print August 6 2012,doi:10.1161/CIRCULATIONAHA.112.123588
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Heart Failure: A PKGarious Balancing Act
- David A. Kass
Circulation. 2012;126:797-799, published online before print July 17 2012,doi:10.1161/CIRCULATIONAHA.112.124909
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Cardiac Fibrosis Revisited by MicroRNA Therapeutics
- Thomas Thum and
- Johan M. Lorenzen
Circulation. 2012;126:800-802, published online before print July 18 2012,doi:10.1161/CIRCULATIONAHA.112.125013
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Exercise Hemodynamics and Risk Assessment in Asymptomatic Aortic Stenosis
- Robert O. Bonow
Circulation. 2012;126:803-805, published online before print July 25 2012,doi:10.1161/CIRCULATIONAHA.112.130591
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Original Articles

Arrhythmia/Electrophysiology

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A Comprehensive Evaluation of Rhythm Monitoring Strategies for the Detection of Atrial Fibrillation Recurrence: Insights From 647 Continuously Monitored Patients and Implications for Monitoring After Therapeutic Interventions
- Efstratios I. Charitos,
- Ulrich Stierle,
- Paul D. Ziegler,
- Malte Baldewig,
- Derek R. Robinson,
- Hans-Hinrich Sievers,
- and Thorsten Hanke
Circulation. 2012;126:806-814, published online before print July 23 2012,doi:10.1161/CIRCULATIONAHA.112.098079
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- CME Course
- Clinical Perspective
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Implantable Cardioverter-Defibrillators Have Reduced the Incidence of Resuscitation for Out-of-Hospital Cardiac Arrest Caused by Lethal Arrhythmias
- Michiel Hulleman,
- Jocelyn Berdowski,
- Joris R. de Groot,
- Pascal F.H.M. van Dessel,
- C. Jan Willem Borleffs,
- Marieke T. Blom,
- Abdenasser Bardai,
- Carel C. de Cock,
- Hanno L. Tan,
- Jan G.P. Tijssen,
- and Rudolph W. Koster
Circulation. 2012;126:815-821, published online before print August 6 2012,doi:10.1161/CIRCULATIONAHA.111.089425
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- Clinical Perspective

Heart Failure

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Effect of QRS Duration and Morphology on Cardiac Resynchronization Therapy Outcomes in Mild Heart Failure: Results From the Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction (REVERSE) Study
- Michael R. Gold,
- Christophe Thébault,
- Cecilia Linde,
- William T. Abraham,
- Bart Gerritse,
- Stefano Ghio,
- Martin St. John Sutton,
- and Jean-Claude Daubert
Circulation. 2012;126:822-829, published online before print July 10 2012,doi:10.1161/CIRCULATIONAHA.112.097709
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- Clinical Perspective
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Low Myocardial Protein Kinase G Activity in Heart Failure With Preserved Ejection Fraction
- Loek van Heerebeek,
- Nazha Hamdani,
- Inês Falcão-Pires,
- Adelino F. Leite-Moreira,
- Mark P.V. Begieneman,
- Jean G.F. Bronzwaer,
- Jolanda van der Velden,
- Ger J.M. Stienen,
- Gerrit J. Laarman,
- Aernout Somsen,
- Freek W.A. Verheugt,
- Hans W.M. Niessen,
- and Walter J. Paulus
Circulation. 2012;126:830-839, published online before print July 17 2012,doi:10.1161/CIRCULATIONAHA.111.076075
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- Clinical Perspective
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MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-β1 Pathway
- Zhenwei Pan,
- Xuelin Sun,
- Hongli Shan,
- Ning Wang,
- Jinghao Wang,
- Jinshuai Ren,
- Shuya Feng,
- Liangjun Xie,
- Chunying Lu,
- Ye Yuan,
- Yang Zhang,
- Ying Wang,
- Yanjie Lu,
- and Baofeng Yang
Circulation. 2012;126:840-850, published online before print July 18 2012,doi:10.1161/CIRCULATIONAHA.112.094524
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- Data Supplement
- Clinical Perspective

Valvular Heart Disease

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Determinants and Prognostic Significance of Exercise Pulmonary Hypertension in Asymptomatic Severe Aortic Stenosis
- Patrizio Lancellotti,
- Julien Magne,
- Erwan Donal,
- Kim O'Connor,
- Raluca Dulgheru,
- Monica Rosca,
- and Luc A. Pierard
Circulation. 2012;126:851-859, published online before print July 25 2012,doi:10.1161/CIRCULATIONAHA.111.088427
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Clinician Update

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Use of the CHA₂DS₂-VASc and HAS-BLED Scores to Aid Decision Making for Thromboprophylaxis in Nonvalvular Atrial Fibrillation
- Deirdre A. Lane and
- Gregory Y.H. Lip
Circulation. 2012;126:860-865, doi:10.1161/CIRCULATIONAHA.111.060061
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Advances in Mechanical Circulatory Support

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Quality of Life and Left Ventricular Assist Device Support
- Jane MacIver and
- Heather J. Ross
Circulation. 2012;126:866-874, doi:10.1161/CIRCULATIONAHA.111.040279
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Images in Cardiovascular Medicine

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Five-Year Optical Coherence Tomography Follow-Up of an Everolimus-Eluting Bioresorbable Vascular Scaffold: Changing the Paradigm of Coronary Stenting?
- Antonios Karanasos,
- Cihan Simsek,
- Patrick Serruys,
- Jurgen Ligthart,
- Karen Witberg,
- Robert-Jan van Geuns,
- George Sianos,
- Felix Zijlstra,
- and Evelyn Regar
Circulation. 2012;126:e89-e91, doi:10.1161/CIRCULATIONAHA.112.110122
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ACCF/AHA Focused Update

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2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update):A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
- 2012 Writing Committee Members,
- Hani Jneid,
- Jeffrey L. Anderson,
- R. Scott Wright,
- Cynthia D. Adams,
- Charles R. Bridges,
- Donald E. Casey, Jr,
- Steven M. Ettinger,
- Francis M. Fesmire,
- Theodore G. Ganiats,
- A. Michael Lincoff,
- Eric D. Peterson,
- George J. Philippides,
- Pierre Theroux,
- Nanette K. Wenger,
- and James Patrick Zidar
Circulation. 2012;126:875-910, published online before print July 16 2012,doi:10.1161/CIR.0b013e318256f1e0
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- Online Data Supplement
- Comprehensive Relationships Table

Circulation Topic Review

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Circulation Editors' Picks: Most Read Articles on the Topic of Cardiovascular Surgery
- The Editors
Circulation. 2012;126:e92-e98, doi:10.1161/CIRCULATIONAHA.112.130914
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Correspondence

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Letter by Vítek et al Regarding Article, “Niacin Inhibits Vascular Inflammation via the Induction of Heme Oxygenase-1”
- Libor Vítek,
- Jana Vaníková,
- and Petr Nachtigal
Circulation. 2012;126:e99, doi:10.1161/CIRCULATIONAHA.112.094508
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Letter by Frans and Koelemay Regarding Article, “Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study”
- Franceline A. Frans and
- Mark J.W. Koelemay
Circulation. 2012;126:e100, doi:10.1161/CIRCULATIONAHA.112.098418
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Letter by Malyar et al Regarding Article, “Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study”
- Nasser M. Malyar,
- Matthias Meyborg,
- and Holger Reinecke
Circulation. 2012;126:e101, doi:10.1161/CIRCULATIONAHA.112.100594
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Response to Letters Regarding Article, “Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study”
- Timothy P. Murphy,
- Joselyn Cerezo,
- Donald E. Cutlip,
- Matthew R. Reynolds,
- Judith G. Regensteiner,
- Emile R. Mohler,
- David J. Cohen,
- Joseph M. Massaro,
- Beth A. Lewis,
- Dr Niki C. Oldenburg,
- Michael W. Steffes,
- Alan T. Hirsch,
- Claudia C. Thum,
- Suzanne Goldberg,
- Michael R. Jaff,
- Anthony J. Comerota,
- Jonathan Ehrman,
- Diane Treat-Jacobson,
- Ulf Bronas,
- M. Eileen Walsh,
- Dalynn T. Badenhop,
- and Tracie Collins
Circulation. 2012;126:e102-e103,doi:10.1161/CIRCULATIONAHA.112.113704
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Corrections

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Correction
Circulation. 2012;126:e104, doi:10.1161/CIR.0b013e31826a93a4
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Correction
Circulation. 2012;126:e105, doi:10.1161/CIR.0b013e31826ae2a0
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Clinical Summaries

Circulation: Clinical Summaries: Original Research Put Into Perspective for the Practicing Clinician

Editorials

Atrial Fibrillation Monitoring: Mathematics Meets Real Life

Out-of-Hospital Cardiac Arrest: Getting Beyond the Tip of the Iceberg

Heart Failure: A PKGarious Balancing Act

Cardiac Fibrosis Revisited by MicroRNA Therapeutics

Exercise Hemodynamics and Risk Assessment in Asymptomatic Aortic Stenosis

Original Articles

Arrhythmia/Electrophysiology

A Comprehensive Evaluation of Rhythm Monitoring Strategies for the Detection of Atrial Fibrillation Recurrence: Insights From 647 Continuously Monitored Patients and Implications for Monitoring After Therapeutic Interventions

Implantable Cardioverter-Defibrillators Have Reduced the Incidence of Resuscitation for Out-of-Hospital Cardiac Arrest Caused by Lethal Arrhythmias

Heart Failure

Effect of QRS Duration and Morphology on Cardiac Resynchronization Therapy Outcomes in Mild Heart Failure: Results From the Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction (REVERSE) Study

Low Myocardial Protein Kinase G Activity in Heart Failure With Preserved Ejection Fraction

MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-β1 Pathway

Valvular Heart Disease

Determinants and Prognostic Significance of Exercise Pulmonary Hypertension in Asymptomatic Severe Aortic Stenosis

Clinician Update

Use of the CHA2DS2-VASc and HAS-BLED Scores to Aid Decision Making for Thromboprophylaxis in Nonvalvular Atrial Fibrillation

Advances in Mechanical Circulatory Support

Quality of Life and Left Ventricular Assist Device Support

Images in Cardiovascular Medicine

Five-Year Optical Coherence Tomography Follow-Up of an Everolimus-Eluting Bioresorbable Vascular Scaffold: Changing the Paradigm of Coronary Stenting?

ACCF/AHA Focused Update

Circulation Topic Review

Circulation Editors' Picks: Most Read Articles on the Topic of Cardiovascular Surgery

Correspondence

Letter by Vítek et al Regarding Article, “Niacin Inhibits Vascular Inflammation via the Induction of Heme Oxygenase-1”

Letter by Frans and Koelemay Regarding Article, “Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study”

Letter by Malyar et al Regarding Article, “Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study”

Response to Letters Regarding Article, “Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study”

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Correction

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Use of the CHA₂DS₂-VASc and HAS-BLED Scores to Aid Decision Making for Thromboprophylaxis in Nonvalvular Atrial Fibrillation