爱思唯尔期刊精选全文

		American Heart Journal
		中文标题: 使用虚拟组织学血管内超声技术评估药物洗脱支架对冠状动脉壁形态学长期作用的分析
		英文标题: Analysis of the long-term effects of drug-eluting stents on coronary arterial wall morphology as assessed by virtual histology intravascular ultrasoun...
		作者: Takashi Kubo MD, PhD, Akiko Maehara MD, Gary S. Mi...
		全文: Background Animal models show impairment of arterial healing after drug-eluting stents (DES) compared with bare-metal stents (BMS). Virtual histology intravascular ultrasound (VH-IVUS) offers an op...

		American Journal of Cardiology
		中文标题: 房颤病人的血栓栓塞
		英文标题: Thromboembolism in Atrial Fibrillation
		作者: Jan Menke MD, Lars Lüthje MD, Andreas Kastrup MD a...
		全文: Thromboembolism is a severe complication in atrial fibrillation. This overview presents thromboembolic disease as a single entity, ranging from stroke through mesenteric ischemia to acute limb ische...

		Journal of Cardiac Failure
		中文标题: 睡眠障碍呼吸与心衰：关注阻塞性睡眠呼吸暂停和持续气道正压通气治疗
		英文标题: Sleep-Disordered Breathing and Heart Failure: Focus on Obstructive Sleep Apnea and Treatment With Continuous Positive Airway Pressure
		作者: Mahdi Chowdhury MD, Suzanne Adams RN, MPH and Davi...
		全文: Background Among patients with heart failure, sleep-disordered breathing is a common problem, with a prevalence ranging from 24% to 76%. Encompassed within the general category of sleep-disordere...

		Heart and Lung
		中文标题: 快速流感检测实验(RIDT)结果为阴性的重症甲型(H1N1)流感成年患者的快速临床诊断：甲型流感诊断...
		英文标题: Rapid clinical diagnosis in fatal swine influenza (H1N1) pneumonia in an adult with negative rapid influenza diagnostic tests (RIDTs): Diagnostic swin...
		作者: Burke A. Cunha MD, Uzma Syed MD, Nardeen Mickail M...
		全文: Background The "herald wave" of the H1N1 pandemic spread from Mexico to the United States in spring 2009. Initially, the epicenter of H1N1 in the United States was in the New York area. Our hospital,...

		Gynecologic Oncology
		中文标题: 用于评估新靶向治疗方法的试验设计
		英文标题: Trial design for evaluation of novel targeted therapies
		作者: John Farley and Peter G. Rose
		全文: Objectives The vast number of novel targeted therapies available for testing in the United States dictates that a more efficient system aimed at identifying promising agents for phase III testing n...

		Translational Research
		中文标题: 失血性低血压的早期生理反应
		英文标题: Early physiologic responses to hemorrhagic hypotension
		作者: Ivo P. Torres Filho, Luciana N. Torres and Roland ...
		全文: The identification of early indicators of hemorrhagic hypotension (HH) severity may support early therapeutic approaches and bring insights into possible mechanistic implications. However, few systema...

		Free Radical Biology and Medicine
		中文标题: 过氧化氢是黄嘌呤氧化酶的主要氧化产物
		英文标题: Hydrogen peroxide is the major oxidant product of xanthine oxidase
		作者: Eric E. Kelley, Nicholas K.H. Khoo, Nicholas J. Hu...
		全文: Xanthine oxidase (XO) is a critical source of reactive oxygen species (ROS) in inflammatory disease. Focus, however, has centered almost exclusively on XO-derived superoxide (O2•−), whereas dire...

		Free Radical Biology and Medicine
		中文标题: MYH基因的一种常见变异与DNA氧化增多及老年性疾病有关
		英文标题: A common mutation of the MYH gene is associated with increased DNA oxidation and age-related diseases
		作者: Caixia Suna, Huimei Chena, Wenwen Guo, Kui Zhang, ...
		全文: We describe a common mutation of the MYH gene, which is involved in the repair of oxidative damage to DNA, and its relationship to age, levels of 8-OHdG, and circulating levels of interleukin-1. We...

		American Journal of Cardiology
		中文标题: 伴与不伴糖尿病的左室射血分数良好的心脏衰竭患者的比较
		英文标题: Comparison of Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction Among Those With Versus Without Diabetes Mellitus
		作者: David Aguilar MD, Anita Deswal MD, MPH, Kumudha Ra...
		全文: Heart failure (HF) with preserved left ventricular ejection fraction (LVEF) and diabetes commonly coexist, but the impact of diabetes on HF outcomes in patients with HF and preserved LVEF has not been...

		Contraception
		中文标题: 早期葡萄胎妊娠：一家大型流产服务机构的经验
		英文标题: Early molar pregnancy: experience in a large abortion service
		作者: Maureen Paul, Suzan Goodman, Juan Felix, Rebekah L...
		全文: Background With 1.1 million US women having first-trimester abortions annually, clinicians have an opportunity to diagnose molar pregnancy early. Early moles, however, may lack “classic” diagnostic...

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甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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