爱思唯尔期刊精选全文

		Seminars in Cancer Biology
		中文标题: 多瘤病毒感染的免疫性：多瘤病毒小鼠模型
		英文标题: Immunity to polyomavirus infection: The polyomavirus–mouse model
		作者: Phillip A. Swanson II, Aron E. Lukacher, and Eva S...
		全文: A ubiquitous clinically silent murine pathogen, polyomavirus has enjoyed long-term co-evolution with the mouse, a highly tractable and genetically and immunologically informative small animal model....

		Contraception
		中文标题: 哺乳期妇女产后应用长效醋酸甲羟孕酮的循证方法
		英文标题: An evidence-based approach to postpartum use of depot medroxyprogesterone acetate in breastfeeding women
		作者: Maria Isabel Rodriguez, and Andrew M. Kaunitz
		全文: Depot medroxyprogesterone acetate (DMPA) is an injectable, progestin-only contraceptive that provides highly effective, long-acting, reversible contraception [1]. Its lack of estrogen makes it an ex...

		Seminars in Perinatology
		中文标题: 重症高血压的治疗
		英文标题: The Management of Severe Hypertension
		作者: Laura A. Magee MD MSc FRCPC FACP, and Peter von Da...
		全文: Although definitions of severe hypertension vary, thresholds of ≥160-170 mm Hg systolic and/or ≥110 mm Hg diastolic are in most common usage. A recent focus has been placed on systolic hypertension gi...

		Gynecologic Oncology
		中文标题: 妇科肿瘤学中的腹腔内镜单孔道微创手术(LESS)：技术与初步报告
		英文标题: Laparoendoscopic single-site surgery (LESS) in gynecologic oncology: Technique and initial report
		作者: Amanda Nickles Fader and Pedro F. Escobar
		全文: Objectives Recent reports suggest that laparoendoscopic single-site surgery (LESS), also known as single-port surgery, is technically feasible in treating a variety of disease processes. The purpos...

		American Journal of Obstetrics and Gynecology
		中文标题: 月经周期在成功妊娠子宫预处理中的作用
		英文标题: A role for menstruation in preconditioning the uterus for successful pregnancy
		作者: Jan J. Brosens MD PhD, Malcolm G. Parker PhD, Angu...
		全文: Menstruation is widely viewed as serving no purpose other than to reinitiate the endometrial cycle in the absence of pregnancy. Yet, it is striking that cyclic endometrial decidualization followed by...

		Frontiers in Neuroendocrinology
		中文标题: 对甾醇和甾体性激素神经保护作用的新见解：seladin-1/DHCR24范例
		英文标题: New insights on the neuroprotective role of sterols and sex steroids: The seladin-1/DHCR24 paradigm
		作者: Alessandro Peri, Giovanna Danza, Susanna Benvenuti...
		全文: In 2000 a new gene, i.e. seladin-1 (for selective Alzheimer’s disease indicator-1) was identified and found to be down regulated in vulnerable brain regions in Alzheimer’s disease. Seladin-1 was con...

		Translational Research
		中文标题: 结核病与宿主代谢：古老的关联与最新的见解
		英文标题: Tuberculosis and host metabolism: ancient associations, fresh insights
		作者: Antje Blumenthal, Flonza Isovski and Kyu Y. Rhee
		全文: Epidemiologic studies have repeatedly identified malnutrition as a risk factor for tuberculosis (TB), which is the leading bacterial cause of deaths worldwide. The biologic basis for this association,...

		American Journal of Medicine
		中文标题: 移植物难题
		英文标题: Transplant Troubles
		作者: Baligh Yehia MD, Ashwini Davison MD and Stephen Si...
		全文: Article Outline Presentation Assessment Diagnosis Management References Presentation Ten years after a successful liver transplant, a patient developed troubling symptoms. A 66-year-old woman p...

		Gastroenterology Clinics of North America
		中文标题: 质子泵抑制剂在上胃肠道出血治疗中的角色
		英文标题: The Role of Proton Pump Inhibitors in the Management of Upper Gastrointestinal Bleeding
		作者: Grigorios I. Leontiadis MD PhD, and Colin W. Howde...
		全文: This article summarizes and appraises the evidence from randomized controlled trials (RCT) and meta-analyses of RCTs on the role of proton pump inhibitors (PPIs) in non-variceal upper gastrointestinal...

		Free Radical Biology and Medicine
		中文标题: 代谢综合征与氧化应激
		英文标题: Metabolic syndrome and oxidative stress
		作者: Katsuyuki Ando and Toshiro Fujita
		全文: Metabolic syndrome is an obesity-associated collection of disorders, each of which contributes to cardiovascular risk. Metabolic syndrome is also associated with overproduction of reactive oxygen sp...

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甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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