爱思唯尔期刊精选全文

		American Journal of Cardiology
		中文标题: 吉兰-巴雷综合征的心血管并发症
		英文标题: Cardiovascular Complications of the Guillain-Barré Syndrome
		作者: Siddharth Mukerji MD, Feras Aloka MD, Muhammad U. ...
		全文: The Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis in young adults and the elderly and an important cause of admission to intensive care units. Manifestations of the...

		Gynecologic Oncology
		中文标题: 目前关于卵巢癌维持治疗证据的综述
		英文标题: A review of the current evidence for maintenance therapy in ovarian cancer
		作者: Talia Foster, T. Michelle Brown, Jane Chang, Hans ...
		全文: Objectives Ovarian cancer (OC) typically is diagnosed at advanced stages, in which the primary goal of therapy is to prolong progression-free survival (PFS) and overall survival (OS). In recent yea...

		Translational Research
		中文标题: 热休克蛋白70基因变异体的相互作用与新疆和田地区维吾尔族人的长寿现象
		英文标题: Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity
		作者: Jinxin Li, Wenquan Niu, Yue Qid, Wufuer Mayila, Pe...
		全文: Mounting evidence suggests that all organisms at the cellular level respond to stress by synthesizing heat shock proteins at the expense of other proteins, and the ability of human cells to respond to...

		Free Radical Biology and Medicine
		中文标题: DJ-1与帕金森疾病和其他老年疾病中氧化应激的预防
		英文标题: DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders
		作者: Philipp J. Kahle, Jens Waak and Thomas Gasser
		全文: Mutations in the PARK7/DJ-1 gene are rare causes of autosomal-recessive hereditary Parkinson's disease. Loss-of-function mutations lead to the characteristic selective neurodegeneration of nigrostri...

		Free Radical Biology and Medicine
		中文标题: 信号传导中的NOX蛋白
		英文标题: Nox proteins in signal transduction
		作者: David I. Brown and Kathy K. Griendling
		全文: The NADPH oxidase (Nox) family of superoxide (O2−) and hydrogen peroxide (H2O2)-producing proteins has emerged as an important source of reactive oxygen species (ROS) in signal transduction. ROS pro...

		American Journal of Cardiology
		中文标题: 经皮冠状动脉介入术放射剂量增大的预测因素
		英文标题: Predictors of Increased Radiation Dose During Percutaneous Coronary Intervention
		作者: Mathew Mercuri MSc, Changchun Xie PhD, Michael Lev...
		全文: Radiation-induced injury is a potential unintended outcome of fluoroscopy-supported cardiology procedures (e.g., percutaneous coronary intervention [PCI]). The injury might be deterministic in nature....

		Contraception
		中文标题: 使用杀精子剂或男用避孕套与重要结构性先天畸形之间的关联
		英文标题: The association between use of spermicides or male condoms and major structural birth defects
		作者: M. Shayne Gallaway, D. Kim Waller, Mark A. Canfiel...
		全文: Background Women may become pregnant while using contraceptives. Commonly used contraceptives containing spermicides may or may not be associated with an increased occurrence of structural birth...

		American Journal of Obstetrics and Gynecology
		中文标题: 根据医学研究院的建议对孕期体重增加结果的系统性回顾：出生体重、胎儿生长和产后体重滞留
		英文标题: A systematic review of outcomes of maternal weight gain according to the Institute of Medicine recommendations: birthweight, fetal growth, and postpar...
		作者: Anna Maria Siega-Riz PhD, Meera Viswanathan PhD, M...
		全文: Article Outline Materials and methods Results Birthweight Low birthweight (defined as <2500 g) Fetal growth: large for gestational age (LGA) and macrosomia LGA defined as >90th percentile Mac...

		Translational Research
		中文标题: 哮喘气道平滑肌靶向治疗
		英文标题: Targeting the airway smooth muscle for asthma treatment
		作者: Blanca Camoretti-Mercado
		全文: Asthma is a complex respiratory disease whose incidence has increased worldwide in the last decade. Currently there is no cure for asthma. Although bronchodilator and anti-inflammatory medications are...

		American Journal of Medicine
		中文标题: 质子泵抑制剂的长期安全性
		英文标题: Long-term Safety Concerns with Proton Pump Inhibitors
		作者: Tauseef Ali MD, David Neil Roberts MD and William ...
		全文: Proton pump inhibitors (PPIs) are among the most widely prescribed medications worldwide. Their use has resulted in dramatic improvements in treatment of peptic ulcer disease and gastroesophageal re...

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甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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