2012女性癌症年会
Ovarian cancer
Investigators from The Cancer Genome Atlas (TCGA) identified elements of a molecular profile for ovarian cancer patients considered cured by standard therapy. Three candidate genes (CYP4B1, CEPT1, CHMP4A) were over-represented in advanced stage women who did not recur within 5 years after primary therapy. A secondary analysis of the optimally cytoreduced patients on GOG 182 concluded that for patients with < 1 cm residual tumor, surgical complexity was not associated with improved OS or PFS. However, if high surgical complexity procedures resulted in microscopic residual, these patients had improved outcomes relative to patients with < 1 cm residual disease achieved with surger
来源: ScienceDirect
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